近日,我们张敏教授发表在Cell Death And Differentiation上题为TRIM21-driven K63-linked ubiquitination of RBM38c, as a novel interactor of BECN1, contributes to DNA damage-induced autophagy的研究论文,发现了一种灵长类特异的RNA结合蛋白RBM38的亚型RBM38c。RBM38c在DNA损伤响应中被激活并发生泛素化,进而促进自噬的启动。
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